animation:seminaires:2019:accueil

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animation:seminaires:2019:accueil [2019/06/25 09:33] – cicalugaanimation:seminaires:2019:accueil [2020/01/16 14:34] (Version actuelle) – [ A maggot becomes a fly : from cell dynamics to epithelial tissue patterning] cicaluga
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 ====== Séminaires/Colloquium 2019 ====== ====== Séminaires/Colloquium 2019 ======
 +
 +===== " A maggot becomes a fly " : from cell dynamics to epithelial tissue patterning =====
 +{{:cbp_ens.jpeg?nolink&200 |}}**04 février 2020 de 14h00 à 15h00** \\
 +COLLOQUIUM Centre Blaise Pascal-Laboratory of Biology and Modeling of the Cell \\
 +Salle des Thèses, ENS Lyon, France \\
 +
 +**François GRANER**  (Complex System and Matter, CNRS & Univ. de Paris-Diderot)
 + \\
 +
 +Organisateurs : \\ 
 +
 +  * Daniel Jost (CNRS/Laboratory of Biology and Modeling of the Cell, de l'ENS de Lyon) \\
 +  * Cerasela Calugaru (Centre Blaise Pascal, ENS de Lyon, France) \\
 +   
 +
 +**Abstract :** \\ 
 +
 +Development, homeostasis and regeneration of tissues result from a
 +complex combination of genetics and mechanics. Our model system is the
 +Drosophila metamorphosis, during which the fly strikingly changes,
 +within a few days, from a rather simple maggot shape to a refined
 +adult shape with wings, legs, antennas, waist, neck, and compound eye.
 +
 +Tremendous progress in experimental techniques now provide access to
 +quantitative cell-scale information within tissues, whether on the
 +cell shapes and shape changes, on cell-cell interaction forces, and on
 +the genes being expressed. To uncover mechanisms governing tissue
 +development, a rigorous multiscale approach is required.
 +
 +The biologist and physicist jointly address several challenges :
 +linking cell-cell interactions with tissue structure; linking
 +cell-level dynamical processes such as cell divisions, deaths and
 +rearrangements, with tissue-level morphogenetical changes; and most
 +important, understanding the interplay between genetics and mechanics,
 +which both contribute to regulate the morphogenesis.
 +
 +
  
 ===== Chemical equilibrium in the Earth's core ===== ===== Chemical equilibrium in the Earth's core =====
 {{:cbp_ens.jpeg?nolink&200 |}}**03 juillet 2019 de 11h00 à 12h00** \\ {{:cbp_ens.jpeg?nolink&200 |}}**03 juillet 2019 de 11h00 à 12h00** \\
 COLLOQUIUM Centre Blaise Pascal-Laboratoire de Géologie \\ COLLOQUIUM Centre Blaise Pascal-Laboratoire de Géologie \\
-Amphi. a définir, ENS Lyon, France \\+Amphi L, ENS Lyon, France \\
  
-**Dario ALFE  **, (Valeo AI)+**Dario ALFE  **  (Department of Earth Sciences and Department of Physics and Astronomy, and London Centre for Nanotechnology, University College London)
  \\  \\
  
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 Using first principles calculations of chemical potentials we put contraints on the equilibrium concentrations of oxygen between liquid iron and a liquid silicate mixture, representative of long lived magma ocean (MO) at the base of the mantle. We show that the presence of a large fraction of oxygen in the core can be explained by a relatively large thermodynamic advantage of partitioning from the MO into the liquid core. Using first principles calculations of chemical potentials we put contraints on the equilibrium concentrations of oxygen between liquid iron and a liquid silicate mixture, representative of long lived magma ocean (MO) at the base of the mantle. We show that the presence of a large fraction of oxygen in the core can be explained by a relatively large thermodynamic advantage of partitioning from the MO into the liquid core.
 We also computed chemical potentials in solid ferropericlase, thought to be one of the main constituents of the Earth's mantle, and found that the current oxygen concentration in the core is lower than its equilibrium concentration, suggesting that the mantle may be continually pumping oxygen into the core, even at the present day. This has important consequences for our understanding of convection in the core, supporting the idea of the presence of a stratified, oxygen rich, layer at the top of the core, which may have been observed in the seismological record. We also computed chemical potentials in solid ferropericlase, thought to be one of the main constituents of the Earth's mantle, and found that the current oxygen concentration in the core is lower than its equilibrium concentration, suggesting that the mantle may be continually pumping oxygen into the core, even at the present day. This has important consequences for our understanding of convection in the core, supporting the idea of the presence of a stratified, oxygen rich, layer at the top of the core, which may have been observed in the seismological record.
- 
  
 ===== Machine learning in atomistic simulations: from reaction pathways to phase diagrams  ===== ===== Machine learning in atomistic simulations: from reaction pathways to phase diagrams  =====
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